Friday, October 21, 2016
There is a new antipsychotic out, Vraylar (cariprazine). I haven't seen anyone who's on it yet, but it targets an interesting symptom. (Okay, it targets receptors, but you know what I mean.) Emotional salience is the sense that something is important. I liken it to the background music in movies, where a dump-ta-DUM signals to the audience that something important just happened. Many psychotic people have delusions without hearing voices, because they find emotional salience in odd places. Random, benign events are highlighted by their brains as Important. They just feel it strongly, sometimes overwhelmingly, that the white car driving past their house has something to do with them. These reinforce each other, and a whole delusional system gets built up.
Posted by Assistant Village Idiot at 2:27 PM