In Praise of Obsessive Men, by Rosemary Hopcroft at Aporia. It is a good summary of one side of this discussion about autism. As it is the side I lean to more, I pass it along.
In short, there is evidence that men are more likely than women to obsessively focus on their chosen area to the exclusion of all else, and this often leads to extraordinary achievement. While the achievements often only benefit the achiever himself, in cognitively demanding areas like science they frequently have tremendous public benefits. Thus, it is likely that extraordinary achievements with the greatest public benefit come disproportionately from obsessive, high IQ men. They deserve our gratitude.
However there are things worth mentioning that come from another side of the discussion. It is generally agreed that women are in general more attentive to social norms and better at social tasks. This, plus conscientiousness are the prime suspects why they do better at schools as they are designed in most places. I suspect we will find exactly what brain structures are affected by genes being turned on or off by hormones as early as conception, but that is a matter for another day. For the moment, I stipulate that this is so. Women would thereby have more backup social systems, so that even if they have autism, it is less impairing, and less noticeable. This would explain why it is less often diagnosed.
Secondly, the overlap of symptoms with OCD or Obsessive-Compulsive Personality Disorder makes diagnosis and research less reliable. I think this is going to be wide open for the next twenty years, as genomic data becomes more available. When we say that something is polygenic, that is even more complicated than we think at first. If there is a variant which makes one 1% more obsessive, it is likely upstream or downstream of variants which make one 0.5% or 2% more obsessive, plus a bunch that are so similar that they also weigh in at about 1%. Each of those is surrounded by nearby SNPs that are similar to others in the population that have a tiny effect or magnifying effect, but most likely no effect at all, yet are along for the ride. And our target gene is just along for the ride on some other trait near it on the chromosome which is also being selected for. It's all going to be ranges and percentages combined with a hundred other ranges or percentages elsewhere. Some of those are going to be autism, some OCD, some simply anxiety, not to mention a hundred other God-only-knows selection events.
Funny thing. The odds for things in genetics are going to turn out looking a lot like the odds for things in real life. What a concept. Because all these conditions are Mendelian only in their extreme and more destructive versions, it is likely that many are going to be rather obsessed, somewhat obsessed, mildly obsessed, and this will be lessened by women who are more likely to say to themselves "This is just too much. It costs too much socially" and back off.
There is a further set of arguments which come from autists who declare that the supposedly scientific claims are weaker than advertised, which they often noticed because the internal experience of autists is ignored and dismissed in favor of that which is objectively measured. There is something to this, but that data is, well, polluted by a very high percentage of the self-diagnosed. When these are female, they borrow heavily from feminist perspectives that science/men/logic itself are antagonistic to women's wisdom. (Which is in turn complicated by women who are striving mightly to argue from an entirely objective and logical perspective. Sigh.) I can only say that I take the point that the holes in the autism mainstream's position are real, but that does not prove that all opposition to it is correct.












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